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Long dark cured leather1/19/2023 ![]() ![]() Recently, two quite different treatments have been reported with improvement of RSS: oral doxycycline and oral gabapentine.ĭoxycycline is a tetracycline with antibiotic and anti-inflammatory effects. We observed some improvement due to topical calcineurin inhibitors but could not control the burning and pain sensations. After 2 weeks a partial remission was noted and further improvement was observed during the next 2 months.įor decades, there was no effective treatment available. Therefore, treatment was switched to oral gabapentine. Oral doxycycline for 4 weeks did not result in any improvement. After 4 months, however there was a relapse that could not be controlled by pimecrolimus ointment anymore. The burning and sometimes itching sensations and the hyperalgesia the patient experienced did not improve much. There was an improvement of the erythema after several weeks due to topical calcineurin inhibitor pimecrolimus. Even two courses of systemic corticosteroids did not improve the situation. He was given topical corticosteroid ointments without improvement. Mycological investigations were negative. (B) Less intense redness on the posterior site.Ī patch test was performed to exclude a contact dermatitis due to topical medical drugs, emulsifiers and preservatives without any positive result. (A) Sharp border between intense erythematous scrotal skin and adjacent skin.
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